Robustness and evolvability in living systems / Wagner, Andreas (2005)  

Public ISBD Titre : Robustness and evolvability in living systems Type de document : livre Auteurs : Wagner, Andreas Editeur : Princeton, New Jersey : Princeton University Press Année de publication : 2005 Collection : Princeton studies in complexity Importance : 367 p. ISBN/ISSN/EAN : 978-0-691-13404-8 Langues : Anglais (eng) Mots-clés : Biological systems  Genomic Instability  Molecular evolution  Mutation (Biology)  Robust control  Stability Résumé : All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness. Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness. Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations. En ligne : http://www.loc.gov/catdir/enhancements/fy0654/2004054936-d.html Robustness and evolvability in living systems [livre] / Wagner, Andreas . - Princeton, New Jersey : Princeton University Press, 2005 . - 367 p.. - (Princeton studies in complexity) . ISBN : 978-0-691-13404-8 Langues : Anglais (eng) Mots-clés : Biological systems  Genomic Instability  Molecular evolution  Mutation (Biology)  Robust control  Stability Résumé : All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness. Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness. Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations. En ligne : http://www.loc.gov/catdir/enhancements/fy0654/2004054936-d.html

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
68458	WAG_09_68458	Livre	Salle des ouvrages	09_Génétique_Evolution	Sorti jusqu'au 25/05/2043

Robustness and evolvability in living systems / Wagner, Andreas (2005)  

Public ISBD Titre : Robustness and evolvability in living systems Type de document : livre Auteurs : Wagner, Andreas Editeur : Princeton, New Jersey : Princeton University Press Année de publication : 2005 Collection : Princeton studies in complexity Importance : 367 p. ISBN/ISSN/EAN : 978-0-691-12240-3 Note générale : 2 ex. Langues : Anglais (eng) Mots-clés : Biological systems  Molecular evolution  Mutation  Robust control  Stability Résumé : All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness. Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness. Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations. [Résumé éditeur] En ligne : http://www.loc.gov/catdir/enhancements/fy0654/2004054936-t.html Robustness and evolvability in living systems [livre] / Wagner, Andreas . - Princeton, New Jersey : Princeton University Press, 2005 . - 367 p.. - (Princeton studies in complexity) . ISBN : 978-0-691-12240-3 2 ex. Langues : Anglais (eng) Mots-clés : Biological systems  Molecular evolution  Mutation  Robust control  Stability Résumé : All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness. Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness. Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations. [Résumé éditeur] En ligne : http://www.loc.gov/catdir/enhancements/fy0654/2004054936-t.html

Exemplaires (2)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
67553	WAG_09_67553	Livre	Salle des ouvrages	09_Génétique_Evolution	Disponible
68263	WAG_09_68263	Livre	Salle des ouvrages	09_Génétique_Evolution	Sorti jusqu'au 25/05/2043

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